[1] Ohio State 49-20 Michigan State [12] 2022-10-08 20:00
Stadion: Spartan Stadium Round: 1
Home Manager: Mel Tucker Away Manager: Ryan Day
Head to Head
| NCAAF | 2021/11/20 17:00 | Michigan State v Ohio State | W | 7-56 |
| NCAAF | 2020/12/05 17:00 | Ohio State v Michigan State | W | 52-12 |
| NCAAF | 2019/10/05 23:30 | Michigan State v Ohio State | W | 10-34 |
| NCAAF | 2018/11/10 17:00 | Ohio State v Michigan State | W | 26-6 |
| NCAAF | 2017/11/11 17:00 | Michigan State v Ohio State | W | 3-48 |
| NCAAF | 2016/11/19 17:00 | Ohio State v Michigan State | W | 17-16 |
| NCAAF | 2015/11/21 20:30 | Ohio State v Michigan State | L | 14-17 |
| NCAAF | 2014/11/09 01:00 | Michigan State v Ohio State | W | 37-49 |
Home History
| NCAAF | 2022/10/01 19:30 | Rutgers v Ohio State | W | 10-49 |
| NCAAF | 2022/09/24 23:30 | Wisconsin v Ohio State | W | 21-52 |
| NCAAF | 2022/09/17 23:00 | Toledo v Ohio State | W | 21-77 |
| NCAAF | 2022/09/10 16:00 | Arkansas State v Ohio State | W | 12-45 |
| NCAAF | 2022/09/03 23:30 | Notre Dame v Ohio State | W | 10-21 |
| NCAAF Bowl Games | 2022/01/01 22:00 | Utah v Ohio State | W | 45-48 |
| NCAAF | 2021/11/27 17:00 | Ohio State v Michigan | L | 27-42 |
| NCAAF | 2021/11/20 17:00 | Michigan State v Ohio State | W | 7-56 |
Away History
| NCAAF | 2022/10/01 19:30 | Michigan State v Maryland | L | 13-27 |
| NCAAF | 2022/09/24 19:30 | Minnesota v Michigan State | L | 34-7 |
| NCAAF | 2022/09/17 23:30 | Michigan State v Washington | L | 28-39 |
| NCAAF | 2022/09/10 20:00 | Akron v Michigan State | W | 0-52 |
| NCAAF | 2022/09/02 23:00 | Western Michigan v Michigan State | W | 13-35 |
| NCAAF Bowl Games | 2021/12/31 00:00 | Pittsburgh v Michigan State | W | 21-31 |
| NCAAF | 2021/11/27 20:30 | Penn State v Michigan State | W | 27-30 |
| NCAAF | 2021/11/20 17:00 | Michigan State v Ohio State | L | 7-56 |