Stadion: Walter J. Zable Stadium at Cary Field Round: 1
Home Manager: Mike London Away Manager: Mark Ferrante
| NCAAF | 2021/10/30 17:00 | William & Mary v Villanova | L | 31-18 |
| NCAAF | 2019/10/05 19:30 | Villanova v William & Mary | W | 35-28 |
| NCAAF FCS | 2018/11/10 18:00 | William & Mary v Villanova | L | 24-17 |
| NCAAF | 2022/11/05 18:00 | Villanova v Towson | L | 3-27 |
| NCAAF | 2022/10/29 17:00 | Hampton v Villanova | W | 10-24 |
| NCAAF | 2022/10/22 19:30 | Albany v Villanova | W | 29-31 |
| NCAAF | 2022/10/15 19:30 | Villanova v Richmond | L | 10-20 |
| NCAAF | 2022/10/01 17:00 | Villanova v Maine | W | 45-20 |
| NCAAF | 2022/09/24 19:30 | Monmouth v Villanova | L | 49-42 |
| NCAAF | 2022/09/17 16:00 | Villanova v Army | L | 10-49 |
| NCAAF | 2022/09/10 17:00 | Villanova v LIU Brooklyn | W | 38-21 |
| NCAAF | 2022/11/05 17:00 | William & Mary v Hampton | W | 20-14 |
| NCAAF | 2022/10/29 17:00 | Rhode Island v William & Mary | W | 30-31 |
| NCAAF | 2022/10/22 20:00 | William & Mary v Towson | W | 44-24 |
| NCAAF | 2022/10/08 19:30 | Delaware v William & Mary | W | 21-27 |
| NCAAF | 2022/10/01 19:30 | William & Mary v Stony Brook | W | 27-10 |
| NCAAF | 2022/09/24 19:30 | Elon v William & Mary | L | 35-31 |
| NCAAF | 2022/09/17 19:30 | William & Mary v Lafayette | W | 34-7 |
| NCAAF | 2022/09/10 22:00 | Campbell v William & Mary | W | 21-37 |