Stadion: Roy Stewart Stadium Round: 1
Home Manager: Dean Hood Away Manager:
| NCAAF | 2021/10/30 22:00 | Murray State v Tennessee State | W | 21-27 |
| NCAAF | 2021/03/21 19:00 | Tennessee State v Murray State | L | 13-35 |
| NCAAF | 2019/10/12 19:00 | Murray State v Tennessee State | L | 31-17 |
| NCAAF | 2018/10/13 18:00 | Tennessee State v Murray State | L | 21-45 |
| NCAAF | 2022/10/22 19:00 | Eastern Illinois v Tennessee State | W | 17-37 |
| NCAAF | 2022/10/15 23:00 | Tennessee State v Tennessee Tech | W | 30-14 |
| NCAAF | 2022/10/08 22:00 | Bethune Cookman v Tennessee State | W | 17-41 |
| NCAAF | 2022/10/01 18:00 | Tennessee State v Lane College Dragons | L | 27-28 |
| NCAAF | 2022/09/17 23:00 | Tennessee State v Middle Tennessee St. | L | 6-49 |
| NCAAF | 2022/09/10 23:00 | Jackson State v Tennessee State | L | 16-3 |
| NCAAF | 2022/09/03 20:00 | Tennessee State v East Washington | L | 29-36 |
| NCAAF | 2021/11/20 17:00 | Tennessee State v Mississippi State | L | 10-55 |
| NCAAF | 2022/10/22 18:00 | Murray State v Lindenwood | L | 18-33 |
| NCAAF | 2022/10/15 20:00 | Murray State v Austin Peay | L | 17-52 |
| NCAAF | 2022/10/08 19:00 | Tennessee Martin v Murray State | L | 45-16 |
| NCAAF | 2022/10/01 23:00 | Murray State v SE Louisiana | L | 14-48 |
| NCAAF | 2022/09/24 21:00 | Eastern Illinois v Murray State | L | 35-21 |
| NCAAF | 2022/09/17 18:00 | Murray State v Ball State | L | 0-31 |
| NCAAF | 2022/09/10 23:00 | Jacksonville State v Murray State | L | 34-3 |
| NCAAF | 2022/09/04 00:00 | Murray State v Texas Tech | L | 10-63 |