Stadion: Value City Arena
Home Manager: Chris Holtmann Away Manager: Matt Crenshaw
| NCAAB | 2022/01/15 20:00 | IUPUI v Wisc Milwaukee | L | 54-89 |
| NCAAB | 2022/01/14 01:00 | IUPUI v Wisc Green Bay | L | 54-69 |
| NCAAB | 2022/01/11 00:00 | Illinois - Chicago v IUPUI | L | 67-65 |
| NCAAB | 2022/01/08 19:00 | IUPUI v Wright State | L | 58-72 |
| NCAAB | 2021/12/22 00:00 | Morehead State v IUPUI | L | 80-52 |
| NCAAB | 2021/12/17 00:00 | Chicago St v IUPUI | L | 61-55 |
| NCAAB | 2021/12/11 00:00 | IUPUI v Tennessee State | L | 44-70 |
| NCAAB | 2021/12/04 17:00 | Oakland v IUPUI | L | 78-45 |
| NCAAB | 2022/01/16 17:00 | Penn State v Ohio State | W | 56-61 |
| NCAAB | 2022/01/14 00:00 | Ohio State v Wisconsin | L | 68-78 |
| NCAAB | 2022/01/09 22:30 | Northwestern v Ohio State | W | 87-95 |
| NCAAB | 2022/01/07 00:00 | Ohio State v Indiana | L | 51-67 |
| NCAAB | 2022/01/03 01:00 | Ohio State v Nebraska | W | 87-79 |
| NCAAB | 2021/12/11 17:00 | Wisconsin v Ohio State | W | 55-73 |
| NCAAB | 2021/12/09 02:00 | Towson v Ohio State | W | 74-85 |
| NCAAB | 2021/12/06 00:30 | Ohio State v Penn State | W | 76-64 |