Stadion: Walter J. Zable Stadium at Cary Field Round: 1
Home Manager: Mike London Away Manager: John Garrett
| NCAAF | 2021/09/04 20:30 | Lafayette v Texas | L | 18-38 |
| NCAAF | 2021/09/04 18:00 | Lafayette v Air Force | L | 14-35 |
| NCAAF | 2021/04/10 16:30 | Lehigh v Lafayette | W | 13-20 |
| NCAAF | 2021/03/27 20:00 | Lafayette v Bucknell | L | 13-38 |
| NCAAF | 2021/03/13 20:30 | Colgate v Lafayette | W | 10-24 |
| NCAAF | 2020/12/26 20:30 | Lafayette v Texas-San Antonio | W | 31-24 |
| NCAAF | 2020/12/05 01:30 | Lafayette v Appalachian St | W | 24-21 |
| NCAAF | 2020/11/28 20:00 | Lafayette v UL Monroe | W | 70-20 |
| NCAAF | 2021/09/04 23:30 | William & Mary v Virginia | L | 0-43 |
| NCAAF | 2021/03/27 17:00 | James Madison v William & Mary | L | 38-10 |
| NCAAF | 2021/03/20 20:00 | Elon v William & Mary | W | 10-31 |
| NCAAF | 2021/03/06 18:00 | William & Mary v Richmond | L | 14-21 |
| NCAAF | 2019/11/23 17:00 | William & Mary v Richmond | W | 21-15 |
| NCAAF | 2019/11/16 18:00 | Towson v William & Mary | L | 31-10 |
| NCAAF | 2019/11/09 18:00 | Rhode Island v William & Mary | W | 19-55 |
| NCAAF | 2019/11/02 18:00 | William & Mary v Elon | W | 31-29 |