| Uruguay - Reserveliga | 2022/06/14 18:00 | Rentistas - Reserve v Defensor Sporting - Reserve | L | 3-1 |
| Uruguay - Reserveliga | 2022/12/05 13:00 | Deportivo Maldonado - Reserve v Defensor Sporting - Reserve | L | 2-1 |
| Uruguay - Reserveliga | 2022/12/01 19:00 | Defensor Sporting - Reserve v Danubio - Reserve | L | 0-5 |
| Uruguay - Reserveliga | 2022/11/24 19:00 | Cerrito - Reserve v Defensor Sporting - Reserve | W | 0-1 |
| Uruguay - Reserveliga | 2022/11/21 19:00 | Nacional de Montevideo - Reserve v Defensor Sporting - Reserve | L | 3-1 |
| Uruguay - Reserveliga | 2022/11/14 12:30 | Defensor Sporting - Reserve v Albion FC - Reserve | W | 5-1 |
| Uruguay - Reserveliga | 2022/11/04 13:00 | Atletico Fenix - Reserve v Defensor Sporting - Reserve | L | 5-0 |
| Uruguay - Reserveliga | 2022/10/25 18:00 | Defensor Sporting - Reserve v Cerro Largo - Reserve | W | 4-0 |
| Uruguay - Reserveliga | 2022/10/11 13:00 | Atletico River Plate - Reserve v Defensor Sporting - Reserve | D | 0-0 |
| Uruguay - Reserveliga | 2022/12/05 19:00 | Rentistas - Reserve v Atletico Fenix - Reserve | W | 1-0 |
| Uruguay - Reserveliga | 2022/11/21 19:00 | Rentistas - Reserve v Atletico River Plate - Reserve | D | 2-2 |
| Uruguay - Reserveliga | 2022/11/14 19:00 | Boston River - Reserve v Rentistas - Reserve | D | 3-3 |
| Uruguay - Reserveliga | 2022/11/10 19:00 | Rentistas - Reserve v Liverpool Montevideo - Reserve | D | 2-2 |
| Uruguay - Reserveliga | 2022/11/08 13:00 | Rentistas - Reserve v Plaza Colonia - Reserve | D | 1-1 |
| Uruguay - Reserveliga | 2022/11/03 18:00 | Montevideo Wanderers - Reserve v Rentistas - Reserve | L | 5-0 |
| Uruguay - Reserveliga | 2022/10/25 18:00 | Rentistas - Reserve v Torque - Reserve | L | 1-2 |
| Uruguay - Reserveliga | 2022/10/17 18:00 | Rentistas - Reserve v Danubio - Reserve | D | 1-1 |