| Guatemala - Reserveliga | 2022/05/04 16:11 | Coban Imperial - Reserve v Santa Lucia FC - Reserve | W | 0-1 |
| Guatemala - Reserveliga | 2022/11/19 21:00 | CSD Municipal - Reserve v Santa Lucia FC - Reserve | L | 2-0 |
| Guatemala - Reserveliga | 2022/11/16 17:00 | Xinabajul - Reserve v Santa Lucia FC - Reserve | L | 3-1 |
| Guatemala - Reserveliga | 2022/09/24 20:00 | CD Achuapa - Reserve v Santa Lucia FC - Reserve | W | 0-1 |
| Guatemala - Reserveliga | 2022/08/31 17:00 | Xelaju - Reserve v Santa Lucia FC - Reserve | D | 1-1 |
| Guatemala - Reserveliga | 2022/08/11 17:00 | Malacateco - Reserve v Santa Lucia FC - Reserve | W | 1-2 |
| Guatemala - Reserveliga | 2022/05/04 16:11 | Coban Imperial - Reserve v Santa Lucia FC - Reserve | W | 0-1 |
| Guatemala - Reserveliga | 2022/04/30 21:20 | Santa Lucia FC - Reserve v Nueva Concepcion Reserves | W | 4-1 |
| Guatemala - Reserveliga | 2022/04/23 21:00 | Xelaju - Reserve v Santa Lucia FC - Reserve | D | 1-1 |
| Guatemala - Reserveliga | 2022/11/20 17:00 | Coban Imperial - Reserve v Xelaju - Reserve | W | 2-1 |
| Guatemala - Reserveliga | 2022/09/24 16:00 | Coban Imperial - Reserve v CSD Municipal - Reserve | L | 0-2 |
| Guatemala - Reserveliga | 2022/08/31 17:00 | Guastatoya - Reserve v Coban Imperial - Reserve | L | 2-1 |
| Guatemala - Reserveliga | 2022/08/10 21:15 | Deportivo Iztapa - Reserve v Coban Imperial - Reserve | W | 1-5 |
| Guatemala - Reserveliga | 2022/08/05 19:07 | Coban Imperial - Reserve v CD Achuapa - Reserve | W | 4-2 |
| Guatemala - Reserveliga | 2022/07/23 21:00 | CSD Municipal - Reserve v Coban Imperial - Reserve | L | 3-0 |
| Guatemala - Reserveliga | 2022/05/04 16:11 | Coban Imperial - Reserve v Santa Lucia FC - Reserve | L | 0-1 |
| Guatemala - Reserveliga | 2022/04/20 20:00 | Deportivo Iztapa - Reserve v Coban Imperial - Reserve | D | 2-2 |