[14] Southampton 4-1 Brentford [12] 2022-01-11 19:45
Stadion: St. Mary’s Stadium Round: 18
Schiedsrichter: Stuart Attwell Home Manager: Ralph Hasenhüttl Away Manager: Thomas Frank
Head to Head
| England - EFL Cup | 2020/09/16 18:45 | Southampton v Brentford | L | 0-2 |
| Freundschaftsspiele - Europa | 2017/07/22 14:00 | Brentford v Southampton | D | 2-2 |
Home History
| England - FA Cup | 2022/01/08 17:30 | Swansea v Southampton | W | 2-3 |
| England - Premier League | 2021/12/28 15:00 | Southampton v Tottenham | D | 1-1 |
| England - Premier League | 2021/12/26 15:00 | West Ham v Southampton | W | 2-3 |
| England - Premier League | 2021/12/15 19:30 | Crystal Palace v Southampton | D | 2-2 |
| England - Premier League | 2021/12/11 15:00 | Arsenal v Southampton | L | 3-0 |
| England - Premier League | 2021/12/04 15:00 | Southampton v Brighton | D | 1-1 |
| England - Premier League | 2021/12/01 19:30 | Southampton v Leicester | D | 2-2 |
| England - Premier League | 2021/11/27 15:00 | Liverpool v Southampton | L | 4-0 |
Away History
| England - FA Cup | 2022/01/08 15:00 | Port Vale v Brentford | W | 1-4 |
| England - Premier League | 2022/01/02 14:00 | Brentford v Aston Villa | W | 2-1 |
| England - Premier League | 2021/12/29 20:15 | Brentford v Manchester City | L | 0-1 |
| England - Premier League | 2021/12/26 20:00 | Brighton v Brentford | L | 2-0 |
| England - EFL Cup | 2021/12/22 19:45 | Brentford v Chelsea | L | 0-2 |
| England - Premier League | 2021/12/10 20:00 | Brentford v Watford | W | 2-1 |
| England - Premier League | 2021/12/05 14:00 | Leeds v Brentford | D | 2-2 |
| England - Premier League | 2021/12/02 19:30 | Tottenham v Brentford | L | 2-0 |