[4] Santos de Guápiles 1-2 Cartagines [5] 2021-11-24 23:00
Stadion: Estadio Ebal Rodriguez Round: 21
Head to Head
| Costa Rica - Primera Division | 2021/09/12 02:00 | Cartagines v Santos de Guápiles | W | 1-2 |
| Costa Rica - Primera Division | 2021/03/09 01:00 | Santos de Guápiles v Cartagines | W | 1-0 |
| Costa Rica - Primera Division | 2021/01/15 02:00 | Cartagines v Santos de Guápiles | L | 1-0 |
| Costa Rica - Primera Division | 2020/11/11 17:00 | Cartagines v Santos de Guápiles | L | 3-0 |
| Costa Rica - Primera Division | 2020/03/01 21:00 | Santos de Guápiles v Cartagines | L | 1-3 |
| Costa Rica - Primera Division | 2020/01/12 17:00 | Cartagines v Santos de Guápiles | D | 2-2 |
| Costa Rica - Primera Division | 2019/09/13 02:00 | Santos de Guápiles v Cartagines | W | 2-1 |
| Costa Rica - Primera Division | 2019/07/21 17:00 | Cartagines v Santos de Guápiles | D | 0-0 |
Home History
| Costa Rica - Primera Division | 2021/11/20 23:00 | AD San Carlos v Santos de Guápiles | W | 2-4 |
| CONCACAF League | 2021/11/03 00:00 | Forge FC v Santos de Guápiles | L | 3-0 |
| Costa Rica - Primera Division | 2021/10/30 22:30 | Santos de Guápiles v Municipal Perez Zeledon | W | 3-2 |
| Costa Rica - Primera Division | 2021/10/27 23:00 | Herediano v Santos de Guápiles | D | 1-1 |
| Costa Rica - Primera Division | 2021/10/24 20:00 | Santos de Guápiles v ADR Jicaral | L | 2-3 |
| CONCACAF League | 2021/10/20 22:00 | Santos de Guápiles v Forge FC | W | 3-1 |
| Costa Rica - Primera Division | 2021/10/17 20:00 | AD Guanacasteca v Santos de Guápiles | W | 1-3 |
| Costa Rica - Primera Division | 2021/10/13 01:00 | Alajuelense v Santos de Guápiles | L | 1-0 |
Away History
| Costa Rica - Primera Division | 2021/11/20 01:00 | Municipal Perez Zeledon v Cartagines | L | 3-0 |
| Costa Rica - Primera Division | 2021/10/31 21:00 | Cartagines v Herediano | L | 0-1 |
| Costa Rica - Primera Division | 2021/10/27 01:00 | Guadalupe FC v Cartagines | D | 1-1 |
| Costa Rica - Primera Division | 2021/10/24 22:00 | Deportivo Saprissa v Cartagines | D | 1-1 |
| Costa Rica - Primera Division | 2021/10/19 17:00 | Cartagines v Sporting San Jose | W | 1-0 |
| Costa Rica - Primera Division | 2021/10/13 00:00 | AD San Carlos v Cartagines | W | 0-1 |
| Costa Rica - Primera Division | 2021/10/03 02:00 | Cartagines v Alajuelense | W | 1-0 |
| Costa Rica - Primera Division | 2021/09/25 20:00 | AD Guanacasteca v Cartagines | L | 2-1 |