Head to Head
| England - National League North | 2021/12/07 19:45 | Guiseley v Southport | W | 0-2 |
| England - National League North | 2020/12/12 15:00 | Guiseley v Southport | L | 4-2 |
| England - National League North | 2019/08/10 14:00 | Southport v Guiseley | W | 3-0 |
| England - National League North | 2019/03/02 15:00 | Guiseley v Southport | W | 0-1 |
| England - National League North | 2019/01/08 19:45 | Southport v Guiseley | W | 1-0 |
| England - National League | 2017/04/01 14:00 | Southport v Guiseley | L | 0-1 |
| England - National League | 2016/10/08 14:00 | Guiseley v Southport | L | 2-1 |
| England - National League | 2016/03/26 15:00 | Southport v Guiseley | W | 2-0 |
Home History
| England - National League North | 2022/01/22 15:00 | Gloucester v Southport | W | 0-1 |
| England - National League North | 2022/01/18 19:45 | Southport v Bradford P A | W | 1-0 |
| England - FA Trophy | 2022/01/15 15:00 | Southport v Solihull Moors | L | 0-3 |
| England - National League North | 2021/12/28 15:00 | Southport v Farsley Celtic | W | 4-0 |
| England - National League North | 2021/12/26 15:00 | Curzon Ashton v Southport | D | 0-0 |
| England - FA Trophy | 2021/12/18 15:00 | Farsley Celtic v Southport | W | 0-3 |
| England - National League North | 2021/12/11 15:00 | Blyth Spartans v Southport | W | 1-2 |
| England - National League North | 2021/12/07 19:45 | Guiseley v Southport | W | 0-2 |
Away History
| England - National League North | 2022/01/25 19:45 | Guiseley v Alfreton Town | W | 3-2 |
| England - National League North | 2022/01/22 15:00 | AFC Fylde v Guiseley | L | 2-1 |
| England - FA Trophy | 2022/01/18 19:45 | Stourbridge v Guiseley | L | 2-0 |
| England - National League North | 2022/01/08 15:00 | Spennymoor Town v Guiseley | L | 2-1 |
| England - National League North | 2022/01/02 15:00 | Guiseley v Farsley Celtic | D | 0-0 |
| England - National League North | 2021/12/28 15:00 | Guiseley v Bradford P A | D | 2-2 |
| England - National League North | 2021/12/21 19:45 | AFC Telford v Guiseley | W | 0-1 |
| England - National League North | 2021/12/11 15:00 | Brackley v Guiseley | L | 1-0 |