| Guatemala - Reserveliga | 2022/09/24 21:00 | CSD Comunicaciones - Reserve v Xinabajul - Reserve | D | 0-0 |
| Guatemala - Reserveliga | 2022/08/31 17:00 | Xinabajul - Reserve v Antigua GFC - Reserve | L | 0-2 |
| Guatemala - Reserveliga | 2022/08/10 17:00 | Xinabajul - Reserve v CD Achuapa - Reserve | L | 1-4 |
| Guatemala - Reserveliga | 2022/09/24 20:00 | CD Achuapa - Reserve v Santa Lucia FC - Reserve | W | 0-1 |
| Guatemala - Reserveliga | 2022/08/31 17:00 | Xelaju - Reserve v Santa Lucia FC - Reserve | D | 1-1 |
| Guatemala - Reserveliga | 2022/08/11 17:00 | Malacateco - Reserve v Santa Lucia FC - Reserve | W | 1-2 |
| Guatemala - Reserveliga | 2022/05/04 16:11 | Coban Imperial - Reserve v Santa Lucia FC - Reserve | W | 0-1 |
| Guatemala - Reserveliga | 2022/04/30 21:20 | Santa Lucia FC - Reserve v Nueva Concepcion Reserves | W | 4-1 |
| Guatemala - Reserveliga | 2022/04/23 21:00 | Xelaju - Reserve v Santa Lucia FC - Reserve | D | 1-1 |
| Guatemala - Reserveliga | 2022/04/20 20:15 | Santa Lucia FC - Reserve v Malacateco - Reserve | W | 1-0 |
| Guatemala - Reserveliga | 2022/04/10 20:00 | Santa Lucia FC - Reserve v Solola FC Reserves | W | 5-0 |